|
KMID : 0644320020080010023
|
|
Journal of Korean Oriental Oncology
2002 Volume.8 No. 1 p.23 ~ p.35
|
|
|
Study on the Toxicity of Hangam-dan(HAD) in Mice
|
|
Kim Hee-Cheol
Song Kee-Cheol
Yoo Hwa-Seung
Cho Jung-Hyo
Lee Yeon-Weol
Son Chang-Gue
Cho Chong-Kwan
Lee Yong-Koo
Choi Byung-Lyul
|
|
|
Abstract
|
|
|
|
This study was carried out to investigate the oral toxicity of HAD in mice. The results were summarized as follows: 1. HAD did not induced any toxicological effect in the body weight changes of mice. 2. HAD(2.5g/kg, 0.25g/kg) treated group were increased as compared with control group in the hematological values of mice. 3. ALT, AST, BUN, creatinine, CPK were not increased in HAD(2.5g/kg, 0.25g/kg) treated group as compared with control group in the serological values of mice. 4. Brain, Heart, Liver, Spleen, Kidney’s weight were not increased in HAD(2.5g/kg, 0.25g/kg) treated group as compared with control group in the organ’s weight of mice. 5. HAD(2.5g/kg, 0.25g/kg) treated group did not induced any toxicological effect in the gross findings in mice’s any organs. 6. HAD(10g/kg , 5g/kg, 2.5g/kg, 1.25g/kg) treated group did not induced any toxicological effect in the histopathological findings in mice’s any organs. 7. HAD(2.5g/ kg, 0.25g/ kg) treated group did not induced any toxicological effect in the histopathological findings in mice’s any organs. From above results, HAD has not toxicological effects to mice.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|
|